113429-86-0 Usage
General Description
[R,(-)]-1-Bromo-2-propanol, also known as 1-Bromopropane-2-ol, is a chemical compound with the molecular formula C3H7BrO. Falling under the category of organobromine compounds, it appears as a clear colorless to yellow liquid. As a chiral compound, it is found in two enantiomers, out of which, the R-isomer has a levorotatory orientation, denoted by the negative sign in its name. It has a molar mass of approximately 153.0 g/mol. The compound is known for its usage in a variety of chemical reactions, specifically in its capacity as an alkylating agent. The safety and handling of the compound need precautions due to its irritating and harmful nature.
Check Digit Verification of cas no
The CAS Registry Mumber 113429-86-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,4,2 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113429-86:
(8*1)+(7*1)+(6*3)+(5*4)+(4*2)+(3*9)+(2*8)+(1*6)=110
110 % 10 = 0
So 113429-86-0 is a valid CAS Registry Number.
113429-86-0Relevant articles and documents
-
Nakajima,T. et al.
, p. 1807 - 1816 (1969)
-
Enantiomerically enriched bifunctional sec-alcohols prepared by Candida antarctica lipase B catalysis. Evidence of non-steric interactions
Rotticci, Didier,Orrenius, Christian,Hult, Karl,Norin, Torbjoem
, p. 359 - 362 (1997)
Transesterification catalysed by Candida antarctica lipase B was used for the preparation of enantiomerically enriched bifunctional sec-alcohols. The enantiomeric ratio, E, for 3-butyn-2-ol was increased from 1.3 to over 500 by adding an easily removable protecting group. Kinetic resolution of bromohydrins and chlorohydrins bearing a halogen on the large substituent showed high enantioselectivity (E >80). On the other hand, halohydrins with the halogen on the medium group showed low E. Large differences in enantioselectivity were found by substituting the halogen atom of 1-halo-2-alkanols by a methyl group. These differences corresponded to more than 2 kcal mol-1 and were ascribed to non-steric interactions.
