113446-26-7Relevant academic research and scientific papers
Asymmetric synthesis of Rauhut-Currier-type esters via Mukaiyama-Michael reaction to acylphosphonates under bifunctional catalysis
Laina-Martín, Víctor,Del Río-Rodríguez, Roberto,Díaz-Tendero, Sergio,Fernández-Salas, Jose A.,Alemán, José
supporting information, p. 13941 - 13944 (2019/01/03)
A highly enantioselective organocatalytic Mukaiyama-Michael reaction of silyloxy dienes and α,β-unsaturated acyl phosphonates under bifunctional organocatalysis is presented. The new reactivity triggered by the catalyst conducted to Rauhut-Currier type es
CHEMISTRY OF ENOL ETHERS. LXXVII. SYNTHESIS OF ACETALS OF PHENYLSUBSTITUTED GLUTACONALDEHYDES
Makin, S. M.,Kruglikova, R. I.,Lonina, N. N.
, p. 847 - 852 (2007/10/02)
The condensation of the acetals of acetophenone and acetaldehyde with enol ethers, as a result of which 2- and 3-phenyl-1,1,3-trialkoxybutanes were obtained, was studied.The acid hydrolysis of the products leads to the formation of 2- and 3-phenylbutenals, from which 2- and 3-phenyl-1-trimethylsilyloxy-1,3-butadienes were obtained by the action of trimethylchlorosilane and triethylamine.The reaction of the silyloxydienes with ethyl orthoformate in the presence of zinc chloride as catalyst gave the monoacetals of α- and β-phenylglutaconaldehydes, which were converted into the corresponding bisacetals by the further action of the orthoformate.
