113451-18-6Relevant academic research and scientific papers
One-pot synthesis of 1,5-diketones catalyzed by barium isopropoxide
Yanagisawa, Akira,Takahashi, Hiroshi,Arai, Takayoshi
, p. 8581 - 8585 (2007)
A tandem cross-coupling reaction of aryl methyl ketones with aromatic aldehydes has been accomplished employing barium isopropoxide as a catalyst, in which barium enolates are generated and then three consecutive reactions (aldol reaction/β-elimination/co
1,5-Diketone synthesis promoted by barium hydride or barium alkoxides
Takahashi, Hiroshi,Arai, Takayoshi,Yanagisawa, Akira
, p. 2833 - 2835 (2006)
A tandem cross-coupling reaction of ketones with aldehydes has been achieved using barium hydride or isopropoxide as a promoter, in which barium enolates are generated in situ and then three successive reactions (aldol reaction-β-elimination-Michael addit
In situ formed acetals facilitated direct Michael addition of unactivated ketones
Koppolu, Srinivasa Rao,Balamurugan, Rengarajan
, p. 1186 - 1192 (2017/02/10)
TfOH-promoted synthesis of 1,5-diketones by the Michael reaction of unactivated ketones with chalcones has been described. Acetals formed under HC(OMe)3/TfOH conditions generate the required enol-equivalents for a smooth Michael reaction. A wide array of symmetrical and unsymmetrical 1,5-diketones has been synthesised.
N-Heterocyclic Carbene-Catalysed Mukaiyama-Michael Reaction and Mukaiyama Aldol/Mukaiyama-Michael Three-Component Coupling Reaction
Nguyen, Kim,Lupton, David W.
, p. 436 - 441 (2017/04/07)
An N-heterocyclic carbene-catalysed Mukaiyama-Michael addition between several trimethylsilyl (TMS) enol ethers and chalcone derivatives has been discovered. In addition, a related reaction cascade involving dehydrative Mukaiyama aldol followed by a Mukaiyama-Michael addition process has been developed. The later reaction can also be achieved as a three-component coupling reaction. The enantioselective variant of these reactions has been examined with homochiral catalysts. Though these catalysts were active, they fail to achieve enantioinduction.
Conversion of α,β-unsaturated ketones to 1,5-diones via tandem retro-Aldol and Michael addition using Co(acac)2 covalently anchored onto amine functionalized silica
Sodhi, Ravinderpal Kour,Paul, Satya,Gupta, Vivek K.,Kant, Rajni
, p. 1944 - 1948 (2015/03/30)
Abstract A new and efficient method has been developed for the conversion of α,β-unsaturated ketones to 1,5-diketones via tandem retro-Aldol and Michael addition in the presence of Co(acac)2 covalently anchored amine functionalized silica [AS-Co(acac)2]. The single crystal X-ray crystallography confirms the formation of 1,5-diketones. This method has been proved to be an attractive alternative to existing methodologies under conventional homogeneous catalysis with the frequent troublesome manipulation and work-up. The AS-Co(acac)2 was found to be highly active and could be recycled for four consecutive runs with slight decrease in activity.
A facile one-pot synthesis of 2,4,6-triarylpyridine in DMSO
Min, Zhen-Li,Yin, Ting-Zi,Hu, Xia-Min
, p. 7977 - 7980 (2015/02/02)
A facile, efficient and practical method for the one-pot synthesis of 2,4,6-triarylpyridines starting from acetophenones, aryl aldehydes and ammonium acetate by the use of catalytic amounts of 40 % potassium hydroxide in dimethyl sulfoxide is presented. T
ELECTROPHILIC REACTIONS OF CARBONYL COMPOUNDS AND THEIR DERIVATIVES I. AMBIDENT HYDROXYALLYL CATIONS AND ELECTROPHILIC CATALYSIS BY ACYL CATIONS IN THE SYNTHESIS OF OXYGEN-CONTAINING HETEROCYCLES FROM CARBONYL COMPOUNDS
Luk'yanov, S. M.,Borodaev, S. V.,Polovinko, S. B.,Starikov, A. G.,Zubkova, O. V.
, p. 1388 - 1396 (2007/10/02)
The two- and three-component condensation of carbonyl compounds in presence of acids leads to pyrylium salts of symmetric and unsymmetric structure, and also to their mixtures.The different courses of these condensations, which may be realized simultaneou
