113452-66-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Furanmethanol, a-(trifluoromethyl)-, (S)is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological activity and ability to be incorporated into new drug development. Its unique structure allows for the creation of innovative and effective medications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Furanmethanol, a-(trifluoromethyl)-, (S)is utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural products that can improve crop protection and yield.
Used in Medical Applications:
2-Furanmethanol, a-(trifluoromethyl)-, (S)is used as a building block in the development of new drugs due to its anti-inflammatory and antioxidant properties. These characteristics make it a potentially valuable compound for treating various medical conditions and promoting overall health.
Used in Industrial Applications:
2-Furanmethanol, a-(trifluoromethyl)-, (S)-'s unique structure and properties also make it useful in various industrial applications, where it can be employed as a versatile building block for the creation of novel materials and products.
Check Digit Verification of cas no
The CAS Registry Mumber 113452-66-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,4,5 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113452-66:
(8*1)+(7*1)+(6*3)+(5*4)+(4*5)+(3*2)+(2*6)+(1*6)=97
97 % 10 = 7
So 113452-66-7 is a valid CAS Registry Number.
113452-66-7Relevant academic research and scientific papers
Drueckhammer, Dale G.,Barbas, Carlos F.,Nozaki, Kenji,Wong, Chi-Huey,Wood, Cynthia Y.,Ciufolini, Marco A.
, p. 1607 - 1611 (1988)
Practical procedures have been developed for the enantioselective reduction of 2-acetylfuran (6a) and 2-(trifluoroacetyl)furan (6b) to the corresponding carbinols (S)-1 and 7b with 88-90percent ee using Thermoanaerobium brockii alcohol dehydrogenase coupled with an NADPH regeneration system.Kinetic resolution of racemic (S)-1 via lipase-catalyzed esterification, followed by cholesterol esterase or lipase-catalyzed hydrolysis of the ester gives (R)-1 with 94percent ee.Conversion of (S)-1 to the dihydropyranones 4 and 5 without racemization has been illustrated.Enantioselectivehydrolysis of N-protected furylglycine methyl esters catalyzed by papain gave the unreacted esters and and the free acids (S form) both in 45percent yield and 97percent ee.The resolved furylglycines are excellent substrates for the synthesis of optically active synthons for alkaloids.
