1134564-19-4Relevant academic research and scientific papers
Substituent effects in regio- And stereoselective ring-opening reaction of aziridines with ET3N·3HF for β-fluoroamine synthesis
Sasaki, Shigeru,Watanabe, Satono,Shiino, Kaori,Yanaka, Yuko,Kaneko, Shiho,Miyamoto, Kana,Yasui, Ayano,Sakaino, Hina,Teramoto, Hiroyoshi,Yamauchi, Takayasu,Higashiyama, Kimio
, p. 823 - 841 (2019/04/26)
This paper discusses the reactivity of various 2-substituted aziridine derivatives. The reaction of chiral 2-aryl-substituted aziridines with triethylamine trihydrofluoride (Et3N·3HF) afforded chiral E-fluoroamines with high stereoselectivity. In contrast
Regio- and stereoselective ring-opening reaction of chiral aziridines: A facile synthesis of chiral β-amino alcohols
Higashiyama, Kimio,Matsumura, Masataka,Kojima, Hiroshi,Yamauchi, Takayasu
experimental part, p. 471 - 485 (2009/06/08)
The reaction of chiral 2-alkylsubstituted aziridines (1a-d) with acetic acid afforded β-amino alcohols with an (S)-chiral center at the β position (with respect to oxygen). In contrast, a reaction of the same chiral aziridines with acetyl chloride followe
