1134565-72-2

Basic information

• Product Name: 1-[(4S,5R)-4,5-dimethyl-2-oxo-4-{2-[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]ethyl}-dihydrofuran-3(2H)-ylidene]ethyl acetate
• CAS NO: 1134565-72-2
• Molecular Weight: 348.483
• Mol File: 1134565-72-2.mol

Chemical Properties

• CAS DataBase Reference: 1-[(4S,5R)-4,5-dimethyl-2-oxo-4-{2-[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]ethyl}-dihydrofuran-3(2H)-ylidene]ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(4S,5R)-4,5-dimethyl-2-oxo-4-{2-[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]ethyl}-dihydrofuran-3(2H)-ylidene]ethyl acetate(1134565-72-2)
• EPA Substance Registry System: 1-[(4S,5R)-4,5-dimethyl-2-oxo-4-{2-[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]ethyl}-dihydrofuran-3(2H)-ylidene]ethyl acetate(1134565-72-2)

Safety Data

• Hazardous Substances Data: 1134565-72-2(Hazardous Substances Data)

Upstream product

• 1134565-38-0 (4S,5R)-3-acetyl-4,5-dimethyl-4-{2-[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]ethyl}-dihydrofuran-2(3H)-one 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Total synthesis of (+)-neomarinone

The first total synthesis of (+)-neomarinone has been achieved by following a concise and convergent route using methyl (R)-lactate and (R)-3-methylcyclohexanone as chiral building blocks. Key steps of the synthesis are the stereocontrolled formation of the two quaternary stereocenters by diastereoselective 1,4-conjugate addition and enolate alkylation reactions, and the construction of the furanonaphthoquinone skeleton by regioselective Diels-Alder reaction between a 1,3-bis(trimethylsilyloxy)-1,3-diene and a bromoquinone. The synthesis proves the relative and absolute stereochemistry of natural neomarinone.