113465-35-3

Basic information

• Product Name: Phenol, 2,6-dimethoxy-4-[2-(3-methyl-5-isoxazolyl)ethenyl]-
• CAS NO: 113465-35-3
• Molecular Formula: C14H15NO4
• Molecular Weight: 261.277
• Mol File: 113465-35-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 2,6-dimethoxy-4-[2-(3-methyl-5-isoxazolyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,6-dimethoxy-4-[2-(3-methyl-5-isoxazolyl)ethenyl]-(113465-35-3)
• EPA Substance Registry System: Phenol, 2,6-dimethoxy-4-[2-(3-methyl-5-isoxazolyl)ethenyl]-(113465-35-3)

Safety Data

• Hazardous Substances Data: 113465-35-3(Hazardous Substances Data)

Upstream product

• 19668-85-0 2-(3-methylisoxazol-5-yl)acetic acid 
• 134-96-3 syringic aldehyde 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 113465-45-5 5-[α-Carboxy-β-(4'-hydroxy-3',5'-dimethoxyphenyl) ethenyl]-3-methylisoxazole 
• 113465-90-0 5-Isoxazoleethanol, α-(4-hydroxy-3,5-dimethoxy phenyl)-3-methyl- 

Downstream Products

• 113465-74-0 (E)-6-(4-hydroxy-3,5-dimethoxy phenyl)hex-5-ene-2,4-dione 
• 113482-91-0 3-[β-(4'-hydroxy-3',5'-dimethoxyphenyl)ethenyl]-5-methylpyrazole 

Relevant articles and documents

Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors

A series of styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles were prepared and found to be dual inhibitors of 5-lipoxygenase and cyclooxygenase in rat basophilic leukemia cells. Compounds from this series also were found to inhibit the in vivo production of LTB4 when dosed orally in rats. Among these compounds, di-tert-butylphenols 19 and 33 exhibit oral activity in various models of inflammation and, most importantly, are devoid of ulcerogenic potential.

Process of preparing pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxygenase inhibitors

The present invention is 3,5-substituted, isoxazoles, pyrazoles, isothiazoles, and analogs thereof having 5-lipoxygenase or cyclooxygenase inhibiting activity or as a sunscreen.