113474-78-5

Basic information

• Product Name: [2-(4-Bromo-benzoylamino)-ethyl]-phosphonic acid dimethyl ester
• CAS NO: 113474-78-5
• Molecular Weight: 336.122
• Mol File: 113474-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(4-Bromo-benzoylamino)-ethyl]-phosphonic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-Bromo-benzoylamino)-ethyl]-phosphonic acid dimethyl ester(113474-78-5)
• EPA Substance Registry System: [2-(4-Bromo-benzoylamino)-ethyl]-phosphonic acid dimethyl ester(113474-78-5)

Safety Data

• Hazardous Substances Data: 113474-78-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 2041-14-7 (2-aminethyl)phosphonic acid 
• 586-75-4 4-chlorobenzoyl chloride 

Relevant articles and documents

Biosynthesis of Natural Products with a P-C Bond, I. - Incorporation of D-Glucose into (2-Aminoethyl)phosphonic Acid in Tetrahymena thermophila

The phosphate-phosphonate rearrangement is tested as a model reaction for the biosynthesis of the P-C bond as alternative to the rearrangement of phosphoenolpyruvate.D-glucose was prepared and added to the growth medium of Tetrahymena thermophila. (2-Aminoethyl)phosphonic acid (AEP) (1) was isolated from the wet cell mass by hydrolysis with 6N HCl and ion exchange chromatography and was derivatized to the crystalline 4-bromobenzamide 26.The amount of -AEP in admixture with unlabeled AEP was up to 43percent, which is not in agreement with an enzymic phosphate-phosphonate rearrangement of dihydroxyacetone phosphate, for which monodeutereated AEP would be expected.For comparison -AEP (31) was prepared starting from 2-amino-ethanol.