113507-43-0

Basic information

• Product Name: N-<(1,1-dimethylethoxy)carbonyl>-4(R)-(4-chlorophenoxy)-(S)-proline
• Synonyms: N-<(1,1-dimethylethoxy)carbonyl>-4(R)-(4-chlorophenoxy)-(S)-proline
• CAS NO: 113507-43-0
• Molecular Weight: 341.791
• Mol File: 113507-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<(1,1-dimethylethoxy)carbonyl>-4(R)-(4-chlorophenoxy)-(S)-proline(CAS DataBase Reference)
• NIST Chemistry Reference: N-<(1,1-dimethylethoxy)carbonyl>-4(R)-(4-chlorophenoxy)-(S)-proline(113507-43-0)
• EPA Substance Registry System: N-<(1,1-dimethylethoxy)carbonyl>-4(R)-(4-chlorophenoxy)-(S)-proline(113507-43-0)

Safety Data

• Hazardous Substances Data: 113507-43-0(Hazardous Substances Data)

Upstream product

• 352-33-0 1-Chloro-4-fluorobenzene 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 

Relevant articles and documents

Synthesis and Pharmacological Activity of Angiotensin Converting Enzyme Inhibitors: N-(Mercaptoacyl)-4-substituted-(S)-prolines

The synthesis of a series of N-(mercaptoacyl)-4-substituted-(S)-prolines (2 and 3) is described.These compounds were evaluated in vitro for inhibition of angiotensin-converting enzyme (ACE), and selected compounds were evaluated in vivo for ACE inhibition.The most potent compounds in vitro are 108, 109, 111, 114, and 116, having relative potencies of 1.0, 1.0, 1.3, 1.1, and 2.6 as compared to the potency of captopril.The most potent compounds in vivo intravenously are 108, 111, 114, 116, 117, and 97.