113519-11-2Relevant academic research and scientific papers
Synthesis of γ-sulfonyl δ-lactones and β-sulfonyl styrenes
Chan, Chieh-Kai,Chen, Yu-Hsin,Hsu, Ru-Ting,Chang, Meng-Yang
, p. 46 - 54 (2016/12/09)
A facile route to the synthesis of γ-sulfonyl lactones 5 and β-sulfonyl styrenes 6 has been developed, achieving moderate to good yields via the (1) NaH mediated Michael addition of β-ketosulfones 3 and methyl acrylate in refluxing THF and (2) NaBH4mediated stereoselective reduction/lactonization of δ-ketoesters 4 in boiling MeOH, or (3) boron trifluoride etherate mediated ring-opening of lactones 5 in MeOH at reflux.
4-(Phenylsulfonyl)butanoic Acid. Preparation, Dianion Generation, and Application to Four-Carbon Chain Extension
Thompson, Charles M.,Frick, Jeffrey A.
, p. 890 - 896 (2007/10/02)
The bishomoenolate dianion of 4-(phenylsulfonyl)butanoic acid was investigated.It was observed the dianion could be generated in greater than 95percent yield with 200 mol percent of n-BuLi at certain concentrations.The dianion was reacted with a variety o
"REMOTE" DIANIONS-I. UTILITY OF 4-PHENYLSULFONYLBUTANOIC ACID IN THE MILD CONVERSION OF ALDEHYDES AND KETONES TO LACTONES.
Thompson, Charles M.
, p. 4243 - 4246 (2007/10/02)
Ketones and aldehydes are converted to lactones in high yield by stepwise treatment with the dianion of 4-phenylsulfonylbutanoic acid and trifluoroacetic anhydride.
