113533-75-8Relevant academic research and scientific papers
Characterization of the LM5 pectic galactan epitope with synthetic analogues of β-1,4-D-galactotetraose
Andersen, Mathias C.F.,Boos, Irene,Marcus, Susan E.,Kra?un, Stjepan K.,Rydahl, Maja Gro,Willats, William G.T.,Knox, J. Paul,Clausen, Mads H.
, p. 36 - 40 (2016)
Plant cell wall glycans are important polymers that are crucial to plant development and serve as an important source of sustainable biomass. The study of polysaccharides in the plant cell wall relies heavily on monoclonal antibodies (mAbs) for localizati
Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II
Cumpstey, Ian,Butters, Terry D.,Tennant-Eyles, Richard J.,Fairbanks, Antony J.,France, Robert R.,Wormald, Mark R.
, p. 1937 - 1949 (2007/10/03)
The fluorescence-labelled disaccharides Glcα(1→3)GlcαOR and Glcα(1→3)ManαOR, both substrates for the glycoprotein-processing enzyme glucosidase II, were synthesised via the use of a n-pentenyl-derived linker at the anomeric position. This allowed incorpor
A solvation-assisted model for estimating anomeric reactivity. Predicted versus observed trends in hydrolysis of n-pentenyl glycosides
Andrews, C. Webster,Rodebaugh, Robert,Fraser-Reid, Bert
, p. 5280 - 5289 (2007/10/03)
An attempt has been made to predict qualitative trends in reactivity at the anomeric center, using N-bromosuccinimide-induced hydrolysis of n-pentenyl glycosides (NPGs) as the experimental model. Calculated relative activation energies based on internal e
n-Pentenyl glycoside based methodology for determining the relative reactivities of variously protected pairs of glycosides
Wilson,Fraser-Reid
, p. 317 - 320 (2007/10/02)
The relative rate of hydrolysis of an α/β anomeric pair of glycosides is generally considered to provide insight into various factors that influence anomeric reactivity. However the fact that such hydrolyses are usually carried out with aqueous acids severely limits the range of substrates that can studied. This limitation is overcome with n-pentenyl glycosides (NPGs) which are hydrolyzed under neutral, oxidative conditions. A procedure is described in which a pair (e.g. α1/β1, α1/β2, β1/β2,etc.) of NPGs is made to compete for an insufficient amount of N-bromosuccinimide, the relative rates of reaction being determined from HPLC peak heights of the unreacted starting materials. Some commonly used acid labile protecting groups, e.g. cyclic acetals and acetyl, are shown to exert profound effects upon relative and absolute rates of anomeric activation.
