113534-16-0 Usage
Uses
Used in Peptide Synthesis:
FMOC-ASN(DOD)-OH is used as a protected amino acid building block for the synthesis of peptides and proteins. The FMOC protecting group ensures that the amino group remains unreacted during the synthesis process, allowing for the precise assembly of peptide sequences.
Used in Controlled Release Systems:
In the pharmaceutical industry, FMOC-ASN(DOD)-OH is utilized as a component in the development of controlled release drug delivery systems. The DOD linker allows for the timed release of the compound, providing a mechanism to regulate the bioavailability and therapeutic effects of peptide-based drugs.
Used in Biotechnology Research:
FMOC-ASN(DOD)-OH is employed as a research tool in biotechnology for the study of protein structure and function. Its ability to selectively modify amino acids provides a means to investigate the impact of specific amino acid alterations on protein activity and stability.
Used in the Development of Peptide-based Therapeutics:
In the field of medicinal chemistry, FMOC-ASN(DOD)-OH is used as a key component in the design and synthesis of peptide-based therapeutics. Its role in the controlled assembly of peptide sequences enables the creation of targeted drugs with specific biological activities, such as enzyme inhibitors or receptor agonists/antagonists.
Check Digit Verification of cas no
The CAS Registry Mumber 113534-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,5,3 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113534-16:
(8*1)+(7*1)+(6*3)+(5*5)+(4*3)+(3*4)+(2*1)+(1*6)=90
90 % 10 = 0
So 113534-16-0 is a valid CAS Registry Number.
113534-16-0Relevant academic research and scientific papers
A New Synthesis of Thymosin α1
Echner, Hartmut,Voelter, Wolfgang
, p. 1095 - 1098 (2007/10/02)
Thymosin α1, an N-acetylated octacosa thymus peptide, isolated first from thymosin fraction 5, is synthesized by the solid phase method using the p-benzyloxybenzyl alcohol/polystyrene/divinylbenzene resin, Nα-Fmoc-amino acids and those with tert-butyl or Boc side chain protection.All couplings are performed with the Bop reagent.The peptide is purified by a combination of gel chromatography and preparative HPLC, its purity checked by amino acid analysis and analytical HPLC, and the biological activity tested by the E-rosette assay.
