113544-19-7Relevant academic research and scientific papers
Iodine-catalyzed intramolecular oxidative thiolation of vinylic carbon-hydrogen bonds via tandem iodocyclization and dehydroiodination: Construction of 2-methylene-3-thiophenones
Zheng, Gang,Ma, Xiaoli,Liu, Bangyu,Dong, Ying,Wang, Mang
supporting information, p. 743 - 748 (2014/04/03)
A metal-free vinylic carbon-hydrogen bond thiolation has been developed. Under the catalysis of iodine (10 mol%), the cyclization of α-alkenoyl ketene dithioacetals afforded a broad range of polyfunctionalized 2-methylene-3-thiophenones in good selectivity with moderate to excellent yields via tandem iodocyclization and dehydroiodination. The synthetic strategy can also be extended to the cyclization of ortho-methylthiophenyl vinyl ketones leading to 2-methylene-3-benzothiophenones.
INTRAMOLECULAR MICHAEL AND ANTI-MICHAEL ADDITIONS OF THIOLATE TO CONJUGATED ACETYLENIC KETONES
Rudorf, Wolf-Dieter,Schwarz, Ralf
, p. 4267 - 4270 (2007/10/02)
The reaction of acetylenic ketones 1 with carbon disulfide in the basic system sodium hydride/dimethylformamide and subsequent intramolecular cyclization to 4H-thiopyran-4-ones 3 and 3(2H)-thiophenones 4 are reported.
