1135467-17-2Relevant academic research and scientific papers
Design and efficient synthesis of amino acid derived 2-substituted imidazoles by palladium-catalyzed cross-coupling reactions
Marek, Ales,Kulhanek, Jiri,Bures, Filip
experimental part, p. 325 - 331 (2009/06/27)
Optically active imidazole derivatives featuring an α-amino acid motif substituted at the 2-position can be prepared in moderate to good yields by Negishi as well as Suzuki-Miyaura cross-couplings as the key synthetic steps. The reaction sequence involves
