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2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid is an organoboron compound with the molecular formula C17H26BNO6. It is characterized by its white to off-white powder form and is sparingly soluble in water, but soluble in organic solvents like acetone and methanol. 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid is widely recognized for its role in organic synthesis, particularly as a reagent in cross-coupling reactions, and for its potential as a potent inhibitor of serine proteases. Its applications extend to pharmaceutical research and drug development, making it a valuable asset in the scientific community.

1135822-19-3

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1135822-19-3 Usage

Uses

Used in Organic Synthesis:
2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid is used as a reagent in cross-coupling reactions for the formation of carbon-carbon bonds, which are crucial in the synthesis of complex organic molecules.
Used in Pharmaceutical Research and Drug Development:
As a potent inhibitor of serine proteases, 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid is utilized in the research and development of new pharmaceuticals, particularly those targeting diseases and conditions where serine protease activity is implicated.
Used in Chemical Research:
In the field of chemical research, 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid serves as a valuable tool for studying the properties and reactions of organoboron compounds, contributing to the advancement of synthetic chemistry and material science.
It is important to handle 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid with care due to its potential harmful effects if ingested, inhaled, or comes into contact with the skin, emphasizing the need for proper safety measures during its use in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1135822-19-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,5,8,2 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1135822-19:
(9*1)+(8*1)+(7*3)+(6*5)+(5*8)+(4*2)+(3*2)+(2*1)+(1*9)=133
133 % 10 = 3
So 1135822-19-3 is a valid CAS Registry Number.

1135822-19-3Relevant academic research and scientific papers

Combined metalation-cross coupling strategies: A synthesis of schumanniophytine by a key biaryl O-carbamate remote anionic fries rearrangement

Macklin, Todd K.,Reed, Mark A.,Snieckus, Victor

supporting information; scheme or table, p. 1507 - 1509 (2009/04/11)

A short synthesis of the alkaloid schumanniophytine (1) starting from simple building blocks and involving directed ortho metalation (DoM), Suzuki-Miyaura cross coupling, and a key ortho-silicon-induced O-carbamate remote anionic Fries rearrangement (3) is described. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

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