1025324-83-7

Upstream product

• 500-99-2 3,5-dimethoxyphenol 
• 88-10-8 N,N-diethylcarbamyl chloride 

Downstream Products

• 1025324-61-1 2-but-2-ynoyl-3,5-dimethoxyphenyl diethylcarbamate 
• 1135822-19-3 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid 
• 909730-04-7 [(3,5-dimethoxyphenyl)ethynyl]triisopropylsilane 
• 1448842-00-9 C₂₄H₃₆N₂O₄Si 
• 1032189-97-1 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate 

Relevant academic research and scientific papers

Combined metalation-cross coupling strategies: A synthesis of schumanniophytine by a key biaryl O-carbamate remote anionic fries rearrangement

A short synthesis of the alkaloid schumanniophytine (1) starting from simple building blocks and involving directed ortho metalation (DoM), Suzuki-Miyaura cross coupling, and a key ortho-silicon-induced O-carbamate remote anionic Fries rearrangement (3) is described. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

Rhodium-Catalyzed C-O Bond Alkynylation of Aryl Carbamates with Propargyl Alcohols

The rhodium-catalyzed alkynylation of aryl carbamates with propargyl alcohols is described. This methodology can provide aryl acetylenes from aryl carbamates via C-O bond activation. The use of propargyl alcohols as alkynylating agents allows the use of a variety of functional groups that are incompatible with organometallic nucleophiles. This reaction also serves to broaden the utility of a carbamate moiety as a convertible ortho directing group.