113592-36-2Relevant academic research and scientific papers
Phosphinic Acid Inhibitors of D-Alanyl-D-alanine Ligase
Parsons, William H.,Patchett, Arthur A.,Bull, Herbert G.,Schoen, William R.,Taub, David,et al.
, p. 1772 - 1778 (2007/10/02)
We report the synthesis of a series of phosphinic acid dipeptide analogues, NH2CH(R1)PO(OH)CH2CH(R2)CO2H, related to DAla-DAla.The best of these compounds are potent, essentially irreversible inhibitors of DAla-DAla ligase, and their
Novel antibacterial agents and potentiators of carbapenem antibiotics
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, (2008/06/13)
New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.
