1136153-56-4

Basic information

• Product Name: N-((1S,2S)-2-hydroxy-1,2-diphenylethyl)-2-methylpropane-2-sulfonamide
• Synonyms: N-((1S,2S)-2-hydroxy-1,2-diphenylethyl)-2-methylpropane-2-sulfonamide
• CAS NO: 1136153-56-4
• Molecular Weight: 333.452
• Mol File: 1136153-56-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((1S,2S)-2-hydroxy-1,2-diphenylethyl)-2-methylpropane-2-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1S,2S)-2-hydroxy-1,2-diphenylethyl)-2-methylpropane-2-sulfonamide(1136153-56-4)
• EPA Substance Registry System: N-((1S,2S)-2-hydroxy-1,2-diphenylethyl)-2-methylpropane-2-sulfonamide(1136153-56-4)

Safety Data

• Hazardous Substances Data: 1136153-56-4(Hazardous Substances Data)

Upstream product

• 196929-85-8 (R)-N-benzylidene-2-methylpropane-2-sulfinamide 
• 1610353-59-7 (1R)-N-(tert-butylsulfonyl)-α-(dimethylphenylsilyl)benzylamine 
• 100-52-7 benzaldehyde 
• 1136153-49-5 C₁₂H₁₇NO₂S 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 

Relevant articles and documents

Stereoretentive Addition of N-tert-Butylsulfonyl-α-Amido Silanes to Aldehydes, Ketones, α,β-Unsaturated Esters, and Imines

Enantioenriched N-tert-butylsulfonyl-α-amido silanes were successfully reacted with aldehydes, ketones, imines, and α,β-unsaturated esters in the presence of a sub-stoichiometric amount of CsF (0.5 equiv) in 1,2-dimethoxyethane (DME) at -20 °C to afford the corresponding coupling products with up to 89 % enantiospecificity in a retentive manner. Keep your cool! Enantioenriched N-tert-butylsulfonyl-α-amido silanes were successfully reacted with aldehydes, ketones, imines, and α,β-unsaturated esters in the presence of a sub-stoichiometric amount of CsF (0.5 equiv) in 1,2-dimethoxyethane (DME) at -20 °C to afford the corresponding coupling products with up to 89 % enantiospecificity in a retentive manner.