1136153-71-3Relevant academic research and scientific papers
Asymmetric synthesis of new chiral N-sulfinyl 2,2-disubstituted aziridines by Grignard additions across α-chloro N-sulfinyl ketimines
Colpaert, Filip,Mangelinckx, Sven,Leemans, Erika,Denolf, Bram,De Kimpe, Norbert
experimental part, p. 3251 - 3258 (2010/08/21)
Reaction of chiral α-chloro N-tert-butanesulfinyl ketimines with Grignard reagents afforded new chiral N-sulfinyl 2,2-disubstituted aziridines in good to excellent diastereomeric ratio (dr up to 98:2). The 1,2,2-trisubstituted aziridines were isolated in
Stereocontrolled synthesis of β-amino alcohols from lithiated aziridines and boronic esters
Schmidt, Frank,Keller, Florian,Vedrenne, Emeline,Aggarwal, Varinder K.
supporting information; experimental part, p. 1149 - 1152 (2009/06/20)
(Chemical Equation Presented) β-Amino alcohols have been prepared with high selectivity by the addition of lithiated aziridines to boronic esters. The regioselectivity of lithiation for aryl aziridines is sensitive to the reaction conditions and to the ba
