113642-40-3Relevant academic research and scientific papers
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands
Magli, Elisa,K?dzierska, Ewa,Kaczor, Agnieszka A.,Bielenica, Anna,Severino, Beatrice,Gibu?a-Tar?owska, Ewa,Kotlińska, Jolanta H.,Corvino, Angela,Sparaco, Rosa,Esposito, Giovanna,Albrizio, Stefania,Perissutti, Elisa,Frecentese, Francesco,Le?niak, Anna,Bujalska-Zadro?ny, Magdalena,Struga, Marta,Capasso, Raffaele,Santagada, Vincenzo,Caliendo, Giuseppe,Fiorino, Ferdinando
, (2021/02/11)
A new series of norbornene and exo-N-hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboximide derivatives was prepared, and their affinities to the 5-HT1A, 5-HT2A, and 5-HT2C receptors were evaluated and compared with a pre
Synthesis and antidepressant activity of 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines
Bosc,Jarry,Carpy,Panconi,Descas
, p. 437 - 442 (2007/10/02)
The synthesis of 20 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines is described. Antidepressant activity was observed in mice using classical screening tests. Structure-activity relationships were studied and correlated with the nature of the aromatic
SYNTHESE ET ACTIVITE ANTI-DEPRESSIVE POTENTIELLE DE NOUVELLES TRIAZINE-1,2,3-ONES-4
Ferrand, Gerard,Dumas, Herve,Depin, Jean-Claude,Chavernac, Gilles
, p. 337 - 346 (2007/10/02)
Synthesis of new 1,2,3-triazin-4-ones as potential anti-depressants.A series of 1,2,3-triazin-4-ones was prepared and examined for potential anti-depressive activity by comparison with trazodone 2.Several of them show a potentiation of the central effects
