113643-84-8Relevant academic research and scientific papers
Facile synthesis and stracture of novel 2,5-disubstituted 1,3,4-selenadiazoles
Hua, Guoxiong,Li, Yang,Fuller, Amy L.,Slawin, Alexandra M.Z.,Woollins, J. Derek
experimental part, p. 1612 - 1618 (2009/08/09)
The reaction of hydrazide with carbony] chloride in the presence of sodium carbonates leads to the corresponding 1,2- diacylhydrazines [1a-t, R 1C(O)NHNHC(O)R2, R1 = aryl, R2 = aryl or alkyl] in moderate to excellent yield (57-90%). The latter reacts with 2,4-diphenyl-l,3-diselenadiphosphetane- 2,4-diselenide (Woollins' reagent, WR) in refluxing toluene to give a series of new 2,5-disubstituted 1,3,4-selenadiazoles (2a-t, 51-99% yield). All compounds were characterized spectroscopically and six compounds were characterized crystalloqraphically. Wiley-VCH Verlag GmbH & Co. KGaA.
An expeditious and convenient one pot synthesis of 2,5-disubstituted-1,3,4-oxadiazoles
Mashraqui, Sabir H.,Ghadigaonkar, Shailesh G.,Kenny, Rajesh S.
, p. 2541 - 2545 (2007/10/03)
A convenient, one pot procedure is reported for the synthesis of a variety of 2,5-disubstituted-1,3,4-oxadiazoles by condensing monoarylhydrazides with acid chlorides in HMPA solvent under the microwave heating. The yields are good to excellent, the process is rapid and does not need any added acid catalyst or dehydrating reagent.
Facile synthesis of symmetric and unsymmetric 1,3,4-oxadiazoles using 2-acyl(or aroyl)pyridazin-3-ones
Park, Yong-Dae,Kim, Jeum-Jong,Chung, Hyun-A,Kweon, Deok-Heon,Cho, Su-Dong,Lee, Sang-Gyeong,Yoon, Yong-Jin
, p. 560 - 564 (2007/10/03)
Symmetric and unsymmetric 1,3,4-oxadiazoles were synthesized in situ from hydrazine hydrate and the corresponding 2-acyl-4,5-dichloropyridazin-3-ones as acylating agents in polyphosphoric acid or BF3·OEt2 in excellent yields.
SYNTHESIS AND PROPERTIES OF FURAN DERIVATIVES. 4. SYNTHESIS OF 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLES CONTAINING FURAN FRAGMENTS
Karakhanov, R. A.,Kelarev, V. I.,Koshelev, V. N.,Morozova, G. V.,Dibi, Ammar
, p. 208 - 218 (2007/10/03)
The condensation of hydrochloride salts of iminoesters of furan acids with hydrazides of carboxylic acids gives 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments.Such compounds are also formed in the condensation of hydrazides of 5-R-furan-2-carboxylic acids with hydrochloride salts of carboxylic acid iminoesters.The reaction of furan acids with hydrazine dihydrochloride in polyphosphoric acid gave symmetrically disubstituted 1,3,4-oxadiazoles containing furan fragments.
