113658-85-8

Basic information

• Product Name: 2,4,6-Trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 2-(1,1-dioxido-3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)ethyl ethyl diester
• Synonyms: Trombodipine; PCA-4230; 2-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)ethyl ethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS NO: 113658-85-8
• Molecular Formula: C₂₁H₂₄N₂O₇S
• Molecular Weight: 448.4895
• Mol File: 113658-85-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 623.2°C at 760 mmHg
• Flash Point: 330.7°C
• Density: 1.327g/cm³
• Vapor Pressure: 1.88E-15mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 2,4,6-Trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 2-(1,1-dioxido-3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)ethyl ethyl diester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 2-(1,1-dioxido-3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)ethyl ethyl diester(113658-85-8)
• EPA Substance Registry System: 2,4,6-Trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 2-(1,1-dioxido-3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)ethyl ethyl diester(113658-85-8)

Safety Data

• Hazardous Substances Data: 113658-85-8(Hazardous Substances Data)

Usage

Main Properties

1. Chemical compound
2. Dihydropyridine structure
3. Benzisothiazol-2-yl group
4. Ethyl diester
5. Molecular formula: C23H27N3O7S
6. Used in medicinal chemistry and drug design

Specific Content

1. Composed of a dihydropyridine structure and a benzisothiazol-2-yl group
2. Ethyl diester of a specific dicarboxylic acid
3. Potential application in developing pharmaceuticals targeting the cardiovascular system or other therapeutic uses
4. Chemical properties and biological activities require further research and testing.

Upstream product

• 626-34-6 ethyl aminocrotonate 
• 75-07-0 acetaldehyde 
• 113658-92-7 2-(1,1,3-trioxo-2,3-dihydro-1,2-benzisothiazol-2-yl)ethyl acetylacetate 
• 6343-81-3 2-(2-hydroxyethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 

Relevant articles and documents

Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines

A series of 1,4-dihydropyridines (DHP) bound to 1,2-benzisothiazol-3-ones were synthesized and evaluated for their ability to inhibit platelet aggregation induced by collagen in human platelet-rich plasma (PRP) and to protect mice against experimental thr