113682-56-7Relevant articles and documents
Enantioselective adsorption in homochiral metal-organic frameworks: The pore size influence
Gu, Zhi-Gang,Grosjean, Sylvain,Br?se, Stefan,W?ll, Christof,Heinke, Lars
, p. 8998 - 9001 (2015)
Uptake experiments in thin films of isoreticular chiral MOFs of type Cu2(Dcam)2(L) with identical stereogenic centers but different pore dimensions show that the enantioselectivity is significantly influenced by the pore size. The hi
Achieving a rare breathing behavior in a polycatenated 2 D to 3 D net through a pillar-ligand extension strategy
Zhao, Xiaoliang,Liu, Fuling,Zhang, Liangliang,Sun, Di,Wang, Rongming,Ju, Zhangfeng,Yuan, Daqiang,Sun, Daofeng
, p. 649 - 652 (2014)
Through a pillar-ligand extension strategy, a rare breathing behavior in polycatenated 2D→3D nets has been achieved. Three variants exhibit interesting sorption properties that range from non-breathing to breathing behaviors, which is influenced by the angles between the pillars and the single honeycomb layers. The increase in pillar length does not lead to an increase in polycatenation multiplicity, which is controlled by the length of intralayer tripodal carboxylate. It also does not induce obviously expanded interlayer separations but occupies much more the free voids, and as a consequence, a smaller pore volume is obtained. This suggests that in 2D→3D polycatenated bilayer metal-organic frameworks, the porosity is not always enhanced by increasing the length of the interlayer pillars with the intralayer linker remaining unchanged. Copyright
Chemical control of spin propagation between heterometallic rings
Faust, Thomas B.,Bellini, Valerio,Candini, Andrea,Carretta, Stefano,Lorusso, Giulia,Allan, David R.,Carthy, Laura,Collison, David,Docherty, Rebecca J.,Kenyon, Jasbinder,MacHin, John,McInnes, Eric J. L.,Muryn, Christopher A.,Nowell, Harriott,Pritchard, Robin G.,Teat, Simon J.,Timco, Grigore A.,Tuna, Floriana,Whitehead, George F. S.,Wernsdorfer, Wolfgang,Affronte, Marco,Winpenny, Richard E. P.
, p. 14020 - 14030 (2011)
We present a synthetic, structural, theoretical, and spectroscopic study of a family of heterometallic ring dimers which have the formula [{Cr 7NiF3(Etglu)(O2CtBu)15} 2(NLN)], in which Etglu is the pentadeprotonated form of the sugar N-ethyl-D-glucamine, and NLN is an aromatic bridging diimine ligand. By varying NLN we are able to adjust the strength of the interaction between rings with the aim of understanding how to tune our system to achieve weak magnetic communication between the spins, a prerequisite for quantum entanglement. Micro-SQUID and EPR data reveal that the magnetic coupling between rings is partly related to the through-bond distance between the spin centers, but also depends on spin-polarization mechanisms and torsion angles between aromatic rings. Density functional theory (DFT) calculations allow us to make predictions of how such chemically variable parameters could be used to tune very precisely the interaction in such systems. For possible applications in quantum information processing and molecular spintronics, such precise control is essential.
Palladium(O)/LiCl Promoted Cross-Coupling Reaction of (4-Pyridyl)stannanes and Aromatic Bromides: Easy Access to Poly(4-pyridyl)-Substituted Aromatics
Fujita, Makoto,Oka, Hiroko,Ogura, Katsuyuki
, p. 5247 - 5250 (1995)
A PdCl2(PPh3)2/LiCl catalyst effectively promoted the cross-coupling reaction of trimethyl(4-pyridyl)stannane and aromatic polybromides to offer easy access to poly(4-pyridyl)-substituted aromatic compounds.
ExTzBox: A Glowing Cyclophane for Live-Cell Imaging
Roy, Indranil,Bobbala, Sharan,Zhou, Jiawang,Nguyen, Minh T.,Nalluri, Siva Krishna Mohan,Wu, Yilei,Ferris, Daniel P.,Scott, Evan Alexander,Wasielewski, Michael R.,Stoddart, J. Fraser
, p. 7206 - 7212 (2018)
The ideal fluorescent probe for live-cell imaging is bright and non-cytotoxic and can be delivered easily into the living cells in an efficient manner. The design of synthetic fluorophores having all three of these properties, however, has proved to be challenging. Here, we introduce a simple, yet effective, strategy based on well-established chemistry for designing a new class of fluorescent probes for live-cell imaging. A box-like hybrid cyclophane, namely ExTzBox·4X (6·4X, X = PF6-, Cl-), has been synthesized by connecting an extended viologen (ExBIPY) and a dipyridyl thiazolothiazole (TzBIPY) unit in an end-to-end fashion with two p-xylylene linkers. Photophysical studies show that 6·4Cl has a quantum yield φF = 1.00. Furthermore, unlike its ExBIPY2+ and TzBIPY2+ building units, 6·4Cl is non-cytotoxic to RAW 264.7 macrophages, even with a loading concentration as high as 100 μM, presumably on account of its rigid box-like structure which prevents its intercalation into DNA and may inhibit other interactions with it. After gaining an understanding of the toxicity profile of 6·4Cl, we employed it in live-cell imaging. Confocal microscopy has demonstrated that 64+ is taken up by the RAW 264.7 macrophages, allowing the cells to glow brightly with blue laser excitation, without any hint of photobleaching or disruption of normal cell behavior under the imaging conditions. By contrast, the acyclic reference compound Me2TzBIPY·2Cl (4·2Cl) shows very little fluorescence inside the cells, which is quenched completely under the same imaging conditions. In vitro cell investigations underscore the significance of using highly fluorescent box-like rigid cyclophanes for live-cell imaging.
Efficient and Rapid Mechanochemical Assembly of Platinum(II) Squares for Guanine Quadruplex Targeting
Garci, Amine,Castor, Katherine J.,Fakhoury, Johans,Do, Jean-Louis,Di Trani, Justin,Chidchob, Pongphak,Stein, Robin S.,Mittermaier, Anthony K.,Fri??i?, Tomislav,Sleiman, Hanadi
, p. 16913 - 16922 (2017)
We present a rapid and efficient method to generate a family of platinum supramolecular square complexes, including previously inaccessible targets, through the use of ball milling mechanochemistry. This one-pot, two-step process occurs in minutes and enables the synthesis of the squares [Pt4(en)4(N∩N)4][CF3SO3]8 (en= ethylenediamine, N∩N = 4,4′-bipyridine derivatives) from commercially available precursor K2PtCl4 in good to excellent yields. In contrast, solution-based assembly requires heating the reagents for weeks and gives lower yields. Mechanistic investigations into this remarkable rate acceleration revealed that solution-based assembly (refluxing for days) results in the formation of large oligomeric side-products that are difficult to break down into the desired squares. On the other hand, ball milling in the solid state is rapid and appears to involve smaller intermediates. We examined the binding of the new supramolecular squares to guanine quadruplexes, including oncogene and telomere-associated DNA and RNA sequences. Sub-micromolar binding affinities were obtained by fluorescence displacement assays (FID) and isothermal titration calorimetry (ITC), with binding preference to telomere RNA (TERRA) sequences. ITC showed a 1:1 binding stoichiometry of the metallosquare to TERRA, while the stoichiometry was more complex for telomeric quadruplex DNA and a double-stranded DNA control.
Construction of non-interpenetrated charged metal-organic frameworks with doubly pillared layers: Pore modification and selective gas adsorption
Sen, Susan,Neogi, Subhadip,Aijaz, Arshad,Xu, Qiang,Bharadwaj, Parimal K.
, p. 7591 - 7598 (2014)
The rigid and angular tetracarboxylic acid 1,3-bis(3,5-dicarboxyphenyl) imidazolium (H4L+), incorporating an imidazolium group, has been used with different pyridine-based linkers to construct a series of non-interpenetrated cationic frameworks, {[Zn2(L)(bpy) 2]·(NO3)·(DMF)6·(H 2O)9}n (1), {[Zn2(L)(dpe) 2]·(NO3)·(DMF)3·(H 2O)2}n (2), and {[Zn2(L)(bpb) 2]·(NO3)·(DMF)3·(H 2O)4}n (3) [L = L3-, DMF = N,N′-dimethylformamide, bpy = 4,4′-bipyridine, dpe = 1,2-di(4-pyridyl) ethylene, bpb = 1,4-bis(4-pyridyl)benzene]. The frameworks consist of {[Zn2(L)]+}n two-dimensional layers that are further pillared by the linker ligands to form three-dimensional bipillared-layer porous structures. While the choice of the bent carboxylic acid ligand and formation of double pillars are major factors in achieving charged non-interpenetrated frameworks, lengths of the pillar linkers direct the pore modulation. Accordingly, the N2 gas adsorption capacity of the activated frameworks (1a-3a) increases with increasing pillar length. Moreover, variation in the electronic environment and marked difference in the pore sizes of frameworks permit selective CO2 adsorption over N2, where 3a exhibits the highest selectivity. In contrast, the selectivity of CO2 over CH4 is reversed and follows the order 1a > 2a > 3a. These results demonstrate that even though the pore sizes of the frameworks are large enough compared to the kinetic diameters of the excluded gas molecules, the electronic environment is crucial for the selective sorption of CO2.
The difference in the CO2adsorption capacities of different functionalized pillar-layered metal-organic frameworks (MOFs)
Gao, Xiang-Jing,Zheng, He-Gen
supporting information, p. 9310 - 9316 (2021/07/12)
The excessive use of fossil energy has caused the CO2concentration in the atmosphere to increase year by year. MOFs are ideal CO2adsorbents that can be used in CO2capture due to their excellent characteristics. Studies of the structure-activity relationship between the small structural differences in MOFs and the CO2adsorption capacities are helpful for the development of efficient MOF-based CO2adsorbents. Therefore, a series of pillar-layered MOFs with similar structural and different functional groups were designed and synthesized. The CO2adsorption tests were carried out at 273 K to explore the relationship between the small structural differences in MOFs caused by different functional groups and the CO2adsorption capacities. Significantly, compound6which contains a pyridazinyl group has a 30.9% increase in CO2adsorption capacity compared to compound1with no functionalized group.
Modular supramolecular dimerization of optically tunable extended aryl viologens
Olesińska, Magdalena,Wu, Guanglu,Gómez-Coca, Silvia,Antón-García, Daniel,Szabó, Istvan,Rosta, Edina,Scherman, Oren A.
, p. 8806 - 8811 (2019/10/16)
Cucurbit[8]uril (CB[8]) mediated assembly of extended aryl viologens (EVs) into optically tunable dimers is reported for the first time. We show that the modular design and synthesis of a new class of π-conjugated viologen derivatives with rigid aromatic
