1137869-91-0

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-1-fluoro-3-methoxy-2-nitro-benzene is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel drug molecules with potential therapeutic applications. Its diverse functional groups allow for further chemical modifications, enhancing the compound's pharmacological properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-1-fluoro-3-methoxy-2-nitro-benzene serves as a precursor in the creation of new agrochemicals, such as pesticides and herbicides. Its unique structure can be tailored to target specific pests or weeds, improving the effectiveness and selectivity of these chemicals in agricultural settings.
Used in Medicinal Chemistry Research:
5-Bromo-1-fluoro-3-methoxy-2-nitro-benzene is utilized as a research compound in medicinal chemistry to explore its potential biological activities and mechanisms of action. Its presence in various chemical libraries aids scientists in understanding its interactions with biological targets, paving the way for the discovery of new therapeutic agents.
Used in Material Science:
5-Bromo-1-fluoro-3-methoxy-2-nitro-benzene also finds applications in material science, where its distinct properties can be leveraged to develop new materials with specific characteristics. For instance, its reactivity and functional groups can be harnessed to create advanced polymers or other materials with tailored properties for various applications.
It is crucial to handle 5-Bromo-1-fluoro-3-methoxy-2-nitro-benzene with care due to its potential hazards to human health and the environment. Proper management and safety measures are essential to mitigate any risks associated with this chemical.

Upstream product

• 67-56-1 methanol 
• 147808-42-2 5-bromo-1,3-difluoro-2-nitro-benzene 

Downstream Products

• 1137869-92-1 3-fluoro-5-methoxy-4-nitrobenzonitrile 
• 1213262-87-3 C₁₅H₁₄BrNO₄S 
• 2090955-25-0 5-bromo-3-methoxy-2-nitroaniline 
• 1807256-50-3 5-bromo-3-fluoro-2-nitrophenol 

Relevant academic research and scientific papers

RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF

The disclosure relates to rifamycin analog compounds, intermediates and precursors thereof, and pharmaceutical compositions capable of inhibiting bacterial growth (e.g., S. aureus growth) and treating bacterial infections (e.g., S. aureus infections). The disclosure further relates to antibody-drug conjugates of rifamycin analog compounds and antibodies, for example, antibodies specific for infectious disease-related targets such as membrane glycoprotein receptor (MSR1), wall teichoic acids (WTA) or Protein A, and methods of use thereof to inhibit bacterial growth and treat bacterial infections.

SOMATOSTATIN MODULATORS AND USES THEREOF

Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or diso

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula (I), wherein R1, R3, R4, R5, L1, and Cy are as defined herein. The present invention also provides compounds, methods for the production of said compounds of the invention, pharmaceutical compositions comprising the same and their use in allergic or inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 and/or interferons. The present invention also methods for the prevention and/or treatment of the aforementioned diseases by administering a compound of the invention.

POLO-LIKE KINASE INHIBITORS

Compounds of the following formula are provided for use with kinases: (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates use

Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors

A series of benzothiazole derivatives as ROCK inhibitors have been discovered. Compounds with good biochemical and cellular potency, and sufficient kinase selectivity have been identified.