113791-29-0

Usage

General Description

The chemical 2-Azetidinone, 3-hydroxy-4,4-dimethyl-1-(1-methylethyl)-3-phenyl-, (R)- is a specific stereoisomer of a compound containing a four-membered azetidinone ring with a hydroxy group, a methyl group, an isopropyl group, and a phenyl group attached. The (R)- designation indicates the stereochemistry of the molecule, referring to the orientation of the substituent groups on the chiral center. This chemical compound may have various applications in pharmaceuticals, organic synthesis, and research, and its specific properties and reactivity depend on its molecular structure and stereochemistry.

Upstream product

• 51804-83-2 N,N-Diisopropyl-2-oxo-2-phenyl-acetamide 
• 51804-83-2 N,N-Diisopropyl-2-oxo-2-phenyl-acetamide 
• 51804-83-2 N,N-diisopropyl-2-oxo-2-phenylacetamide 

Relevant academic research and scientific papers

Formation of a Chiral β-Lactam by Photocyclisation of an Achiral Oxo Amide in its Chiral Crystalline State

Chiral crystals of the achiral oxo amide N,N-di-isopropylphenylglyoxylamide, prepared in large quantities, were irradiated in the solid state to give the optically active β-lactam 3-hydroxy-1-isopropyl-4,4-dimethyl-3-phenylazetidin-2-one in high optical and chemical yields.

X-ray structural studies of chiral β-lactam formation from an achiral oxo amide using the chiral-crystal environment

Chiral crystals of the achiral oxo amide 1, prepared in large quantities, were irradiated in the solid state to give the optically active β-lactam 2 in high optical and chemical yields. The asymmetric induction mechanism has been elucidated by X-ray struc

Formation of Chiral β-Lactams by Photocyclisation of Achiral N,N-Diisopropylarylglyoxylamides in their Chiral Crystalline Form

A variety of N,N-diisopropylarylglyoxylamides formed chiral crystals in which the originally symmetrical molecules were arranged in a chiral form.Photoreaction of the chiral crystals gave optically active β-lactam derivatives.

SELECTIVE REACTIONS IN THE SOLID STATE AND ORGANIC SOLID-SOLID REACTIONS

Since guest molecules in a host-guest complex are arranged regularly and are packed closely, reaction of the guest in the complex is expected to proceed selectively and efficiently in the solid state.When the host compound is chiral, reaction of the guest would proceed enantioselectively.Some such reactions were studied.Furthermore, some usual organic reactions were found to proceed in the solid state.In some cases, organic solid state reactions proceeded more selectively and much faster than in solution.Such solid-solid reactions were also investigated.