113795-41-8Relevant academic research and scientific papers
High yielding alkylations of unactivated sp3 and sp2 centres with alkyl-9-BBN reagents using an NHC-based catalyst: Pd-PEPPSI-IPr
Valente, Cory,Baglione, Sylvia,Candito, David,O'Brien, Christopher J.,Organ, Michael G.
, p. 735 - 737 (2008/09/17)
High yielding, room temperature cross couplings of unactivated alkyl bromides and aryl bromides/chlorides with alkyl-9-BBN reagents has been achieved using an NHC-based catalyst (Pd-PEPPSI-IPr) via a general, functional-group tolerant and easily implemented protocol. The Royal Society of Chemistry.
Synthesis and Hypolipidemic Activity of 2-Substituted Isobutyric Acid Derivatives
Morishita, Shin-ichi,Saito, Takashi,Hirai, Yasuharu,Shoji, Masamichi,Mishima, Yasuhiro,Kawakami, Masato
, p. 1205 - 1209 (2007/10/02)
A series of 2-substituted isobutyric acid derivatives have been synthesized and evaluated as hypolipidemic agents.Compounds 11 and 20 were found to decrease the level of plasma total cholesterol in experimental hyperlipidemic rats to a greater extent than clofibrate (CF) and to increase the level of plasma high-density lipoprotein cholesterol to the same extent as gemfibrozil (GF).Increase in liver weight caused by these compounds were less than those with CF and GF.
