113795-40-7

Upstream product

• 100-66-3 methoxybenzene 
• 21389-46-8 6-phenylhexanoyl chloride 
• 5581-75-9 6-phenylhexanic acid 
• 768-56-9 4-Phenylbut-1-ene 
• 139488-44-1 mercapto-1-(4’-methoxyphenyl)ethanone 

Downstream Products

• 113795-41-8 1-methoxy-4-(6-phenylhexyl)benzene 
• 113795-08-7 2,2-Dimethyl-5-[4-(6-phenyl-hexyl)-phenoxy]-pentanoic acid 
• 113795-32-7 1-(3-Bromo-propoxy)-4-(6-phenyl-hexyl)-benzene 
• 113795-46-3 4-(6-Phenyl-hexyl)-phenol 

Relevant academic research and scientific papers

A metal-free desulfurizing radical reductive C-C coupling of thiols and alkenes

An intermolecular reductive C-C coupling of electrophilic alkyl radicals and alkenes has been developed. Thiols were used as both hydrogen-donating reagents and alkyl radical precursors in the presence of triethyl phosphite and radical initiator. A wide range of alkenes, including styrenes, and aliphatic olefins were well tolerated in this transformation. Mechanistic studies indicated that a phosphite promoted radical desulfurization of thiols to access electrophilic alkyl radicals and a radical chain propagation process may be involved in this transformation.

Synthesis and Hypolipidemic Activity of 2-Substituted Isobutyric Acid Derivatives

A series of 2-substituted isobutyric acid derivatives have been synthesized and evaluated as hypolipidemic agents.Compounds 11 and 20 were found to decrease the level of plasma total cholesterol in experimental hyperlipidemic rats to a greater extent than clofibrate (CF) and to increase the level of plasma high-density lipoprotein cholesterol to the same extent as gemfibrozil (GF).Increase in liver weight caused by these compounds were less than those with CF and GF.