113798-80-4

Basic information

• Product Name: 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)-
• Synonyms: 1,4-Dioxaspiro[4.5]decane-2-methanol, (2R)-;1,4-Dioxaspiro[4.5]decane-2-methanol, (R)-;(2R)-1,4-Dioxaspiro[4.5]decane-2-methanol;(R)-1,4-Dioxaspiro[4.5]decane-2-methanol
• CAS NO: 113798-80-4
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.22
• Mol File: 113798-80-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 248.3±0.0 °C(Predicted)
• Appearance: /
• Density: 1.13
• PKA: 14.21±0.10(Predicted)
• CAS DataBase Reference: 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)-(113798-80-4)
• EPA Substance Registry System: 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)-(113798-80-4)

Safety Data

• Hazardous Substances Data: 113798-80-4(Hazardous Substances Data)

Usage

General Description

1,4-Dioxaspiro[4.5]decane-2-methanol, (R)- is a chemical compound with a complex and specific structure. 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)- belongs to the class of spiroketals, which are cyclic organic compounds containing a spirotetrahydrofuran ring system. The (R)- designation indicates that this compound has a specific stereochemistry, meaning that its chemical structure has a specific orientation of atoms in space. 1,4-Dioxaspiro[4.5]decane-2-methanol, (R)- may have applications in various chemical and pharmaceutical processes due to its unique structure and properties. Its potential uses could include serving as a building block for the synthesis of other complex organic molecules or as a starting material for the production of pharmaceutical drugs.

Upstream product

• 95335-91-4 1,4-dioxaspiro[4.5]decane-2-methanol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 188303-56-2 (R)-2-(3-Methoxy-benzyloxymethyl)-1,4-dioxa-spiro[4.5]decane 

Relevant articles and documents

Application of pig liver esterase catalyzed transesterification in organic media to the kinetic resolution of glycerol derivatives

The PLE/MPEG catalyzed transesterification of the glycerol ketals rac-1a and rac-1d-f with vinyl propionate in toluene proceeded with good selectivities (E=24-34) and gave the enantiomerically enriched S-alcohols 1a and 1d-f, and the S-esters 2a and 2d-f. High selectivities (E=99 and E≥200) were observed in the transesterification of the glycerol ether rac-3 and its desoxy analog rac-5, both having a secondary hydroxy group, with PLE/MPEG. In transesterifications in organic media PLE exhibited a much higher enantioselectivity than in hydrolysis in water.

EFFICIENT RESOLUTION OF SECONDARY ALCOHOLS, CYANOHYDRINS, AND GLYCEROL ACETALS BY COMPLEXATION WITH THE HOST DERIVED FROM TARTARIC ACID

Some title hydroxy compounds were resolved efficiently by complexation with the host compounds derived from tartaric acid.