1138-58-5

Usage

Uses

Used in Pharmaceutical Industry:
4-(N-Butoxy)benzenesulphonamide is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties.
Used in Agrochemical Industry:
4-(N-Butoxy)benzenesulphonamide is used as an intermediate in the synthesis of agrochemicals, particularly for its potential applications as a herbicide, fungicide, and insecticide, helping to control and manage pests and diseases in agriculture.
Used in Antimicrobial Applications:
4-(N-Butoxy)benzenesulphonamide is studied for its antimicrobial properties and is used as a potential antibacterial agent, offering a possible solution for combating bacterial infections.
Used in Material Science:
4-(N-Butoxy)benzenesulphonamide may have applications in the field of material science, where its unique chemical structure could contribute to the development of new materials with specific properties.
Used as a Corrosion Inhibitor:
4-(N-Butoxy)benzenesulphonamide has potential applications as a corrosion inhibitor, providing protection against the degradation of materials in various industrial settings.

InChI:InChI=1/C10H15NO3S/c1-2-3-8-14-9-4-6-10(7-5-9)15(11,12)13/h4-7H,2-3,8H2,1H3,(H2,11,12,13)

Upstream product

• 1126-79-0 n-butyl phenyl ether 
• 1138-56-3 4-butoxybenzene-sulfonyl chloride 
• 109-65-9 1-bromo-butane 
• 1576-43-8 4-hydroxybenzenesulphonamide 

Downstream Products

• 68668-50-8 (4-butoxy-benzenesulfonyl)-carbamic acid ethyl ester 
• 91908-89-3 N-(4-butoxy-benzenesulfonyl)-N'-methyl-urea 
• 1326777-54-1 N-((4-butoxyphenyl)sulfonyl)-3',4'-dichloro-[1,1'-biphenyl]-3-carboxamide 
• 206065-86-3 5-((4-n-butoxybenzene)sulfonylcarbamoyl)-3-(2,4-dichlorobenzyl)-2-methylindole 
• 100862-37-1 N-(4-butoxy-benzenesulfonyl)-N'-propyl-urea 

Relevant academic research and scientific papers

A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

A series of benzene sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors which incorporate lipophilic 4-alkoxy- and 4-aryloxy moieties, together with several derivatives of ethoxzolamide and sulfanilamide are reported. These derivatives were investi

Synthesis and cytotoxic evaluation of substituted sulfonyl-n- hydroxyguanidine derivatives as potential antitumor agents

A series of sulfonyl-N-hydroxygnanidine derivatives was designed and synthesized for cytotoxic evaluation as potential anticancer agents on the basis of the lead compound LY-181984. Replacement of the ureido moiety of the lead compound with hydrexyguanidine provided a stable cytotoxic agent. The conformation of sulfonyl-N-hydroxyguanidine derivatives, such as N-(4- chlorophenyl-)-N-[(benzo[2,3]thiadiazol-4-yl)sulfonyl]-N-hydroxyguanidine (4g), investigated utilizing HMBC NMR, theoretical calculations, and X-ray crystallography, indicated stacking of the two aromatic rings. The derivatives were evaluated for in vitro cytoxicity against five human tumor cell lines, including HepG2, TSGH 8302, COLO 205, KB, and MOLT-4. The cytotoxic activities of the derived compounds against the human tumor cell lines were equal to or greater than that of the lead compound. N-(4- Chlorophenyl)-N'-[[3,5-dichloro-4-(4-nitrophenoxy)phenyl]sulfonyl].N- hydroxyguanidine (4n) and N-(4-chlorophenyl)-N'-[[3,5-dichloro4-(2-chloro-4- nitrophenoxy)phenyl]sulfonyl]-N-hydroxyguanidine (40) exhibited the greatest growth inhibition of solid tumor cell lines. Compound 40 was found to possess antitumor activity against murine K1735/M2 melanoma xenografts.

Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals

The invention relates to sulfonamido- and sulfonamido-carbonylpyridine-2-carboxa of the formula I STR1 and their use as pharmaceuticals, in particular against fibrotic diseases.

Acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides, processes for their preparation and their use as medicaments

The invention relates to acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides of the formula I STR1 in which ______________________________________A = R3 and B = X--NR5 R6 orB = R3 and A = X--NR5 R6.______________________________________ The compounds are suitable as medicaments against fibrotic diseases.