113808-84-7Relevant academic research and scientific papers
PYRAZOL DERIVATIVES
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Page/Page column 52, (2009/02/11)
The invention is concerned with novel pyrazol derivatives of formula (I), wherein R1, R2, R3, R4, X and Y are as defined herein, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor and/or CCR-5 receptor and can be used as medicaments.
Cyclic AMP-specific phosphodiesterase inhibitors
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, (2008/06/13)
Pyrazole compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as
