113810-79-0

Basic information

• Product Name: 5-Hexen-2-one, 5-nitro- (9CI)
• Synonyms: 5-Hexen-2-one, 5-nitro- (9CI)
• CAS NO: 113810-79-0
• Molecular Formula: C₆H₉NO₃
• Molecular Weight: 143.14056
• Product Categories: ACETYLGROUP
• Mol File: 113810-79-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Hexen-2-one, 5-nitro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexen-2-one, 5-nitro- (9CI)(113810-79-0)
• EPA Substance Registry System: 5-Hexen-2-one, 5-nitro- (9CI)(113810-79-0)

Safety Data

• Hazardous Substances Data: 113810-79-0(Hazardous Substances Data)

Upstream product

• 109-49-9 5-Hexen-2-one 

Downstream Products

• 958658-48-5 2-methyl-2-(3-nitro-4-phenylbutyl)-1,3-dioxolane 
• 32776-14-0 1-phenyl-hexane-2,5-dione 
• 50397-92-7 3-methyl-2-phenylcyclopent-2-en-1-one 
• 1128-08-1 dihydro-cis-jasmone 
• 7018-92-0 2,5-Undecanedione 

Relevant articles and documents

A Modular and Diastereoselective 5 + 1 Cyclization Approach to N-(Hetero)Aryl Piperidines

A new general de novo synthesis of pharmaceutically important N-(hetero)aryl piperidines is reported. This protocol uses a robustly diastereoselective reductive amination/aza-Michael reaction sequence to achieve rapid construction of complex polysubstituted ring systems starting from widely available heterocyclic amine nucleophiles and carbonyl electrophiles. Notably, the diastereoselectivity of this process is enhanced by the presence of water, and DFT calculations support a stereochemical model involving a facially selective protonation of a water-coordinated enol intermediate.