113951-09-0

Basic information

• Product Name: 1,3,4,6-tetra-O-acetyl-2-N-(4-methoxy)benzoyl-2-deoxy-β-D-glucopyranose
• Synonyms: 1,3,4,6-tetra-O-acetyl-2-N-(4-methoxy)benzoyl-2-deoxy-β-D-glucopyranose
• CAS NO: 113951-09-0
• Molecular Weight: 481.456
• Mol File: 113951-09-0.mol

Chemical Properties

• CAS DataBase Reference: 1,3,4,6-tetra-O-acetyl-2-N-(4-methoxy)benzoyl-2-deoxy-β-D-glucopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,6-tetra-O-acetyl-2-N-(4-methoxy)benzoyl-2-deoxy-β-D-glucopyranose(113951-09-0)
• EPA Substance Registry System: 1,3,4,6-tetra-O-acetyl-2-N-(4-methoxy)benzoyl-2-deoxy-β-D-glucopyranose(113951-09-0)

Safety Data

• Hazardous Substances Data: 113951-09-0(Hazardous Substances Data)

Upstream product

• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 51471-40-0 6-(hydroxymethyl)-3-[4-methoxybenzylideneamino]tetrahydropyran-2,4,5-triol 
• 5432-46-2 1,3,4,6-tetra-O-acetyl-D-glucosamine hydrochloride 
• 100-07-2 4-methoxy-benzoyl chloride 
• 7597-81-1 1,3,4,6-tetra-O-acetyl-2-deoxy-2-(4-methoxybenzylidene)amino-β-D-glucopyranose 

Relevant articles and documents

Synthesis of NAG-thiazoline-derived inhibitors for β-N-acetyl-d-hexosaminidases

Abstract β-N-Acetyl-d-hexosaminidases are responsible for the metabolism of glycoconjugates in diverse physiological processes that are important targets for medicine and pesticide development. Fourteen new NAG-thiazoline derivatives were synthesized by cyclization and click reaction using d-glucosamine hydrochloride as the starting material. All the compounds created were characterized by NMR and HRMS spectra. A preliminary bioassay, using four enzymes from two β-N-acetyl-d-hexosaminidase families, showed that most of the compounds synthesized exhibit selective inhibition of GH84 β-N-acetyl-d-hexosaminidase. Among the compounds tested, compounds 5a (IC50=12.6 μM, hOGA) and 5e (IC50=12.5 μM, OfOGA) proved to be a highly selective and potent inhibitor.

Glucosamide compound and preparation and application thereof

The invention relates to a glucosamide compound and a preparation method thereof. The glucosamide compound has a structure as shown in the formula (I). In the formula (I), R is methoxy group, nitro group, amino-group, hydroxyl group, C1-4 alkyl group or halogen, n is the number of substituent groups, and n is 1 or 2. The glucosamide compound is simple to prepare, has excellent plant induced resistance activity, and can be used as a plant induced resistance agent for controlling cucumber bacterial angular leaf spot, cucumber target leaf spot and tomato late blight. The invention also relates to a plant induced resistant agent containing the compound.