1139588-27-4

Basic information

• Product Name: N,5-diphenyl-4,5-dihydroisoxazol-3-amine
• CAS NO: 1139588-27-4
• Molecular Weight: 238.289
• Mol File: 1139588-27-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,5-diphenyl-4,5-dihydroisoxazol-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,5-diphenyl-4,5-dihydroisoxazol-3-amine(1139588-27-4)
• EPA Substance Registry System: N,5-diphenyl-4,5-dihydroisoxazol-3-amine(1139588-27-4)

Safety Data

• Hazardous Substances Data: 1139588-27-4(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 103-84-4 Acetanilid 
• 3056-73-3 cinnamanilide 

Relevant articles and documents

Green synthesis of isoxazoline derivatives using microwave irradiation and their antifungal activity

Microwave irradiation method was used for synthesis of isoxazolines. Claisen Schmidt reaction of different aromatic aldehydes with acetanilide gave acrylamides (1a-1h) which on further reaction with hydroxylamine hydrochloride (in the presence of sodium hydroxide) afforded isoxazolines (2a-2h). Physical data of all the synthesized compounds were recorded. Isoxazolines were characterized by their IR and 1H NMR spectra. All the synthesized isoxazolines were screened for their antifungal activity against fungi namely Drechslera maydis and Rhizoctonia solani isolated from maize. Isoxazolines having chloro substitution on benzene ring found to be most effective followed by fluoro and nitro substituted compounds. None of the compound was registered as effective as Bavistin.