113965-60-9Relevant articles and documents
INDOLE DERIVATIVES AND THEIR USE AS THYROID RECEPTOR LIGANDS
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Page/Page column 36, (2008/06/13)
The invention provides compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, (I) wherein R1, R2, R3, R4, R5, R6, Y and W are as defined in the specification. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist.
NOVEL PHARMACEUTICAL COMPOSITIONS
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Page/Page column 45-46, (2008/06/13)
The invention provides the use of compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, for the manufacture of a medicament for the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification. The invention also provides compounds of formula (Ia) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, formula (Ia) wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification.
Displacement of an Aromatic Nitro Group using Phenoxides
Sammes, P. G.,Thetford, D.,Voyle, M.
, p. 1373 - 1374 (2007/10/02)
1,4-dinitrobenzene undergoes nucleophilic substitution with sodium phenoxide and several hindered 2,6-disubstituted phenoxides to afford diphenyl ethers.