113965-66-5Relevant articles and documents
Synthesis of (Rc,Ss)-1,1,1-trifluoro-3-(p-molylsulfinyl)-2-propanol by an asymmetric reduction with a yeast, Yamadazyma farinosa, as a key-step
Sakai, Atsushi,Bakke, Mikio,Ohta, Hiromichi,Kosugi, Hiroshi,Sugai, Takeshi
, p. 1255 - 1256 (2007/10/03)
(Rc,Ss)-1,1,1-trifluoro-3-(p-tolysulfinyl)-2-propanol (>99% e.e.), an important reagent for the asymmetric protonation of substituted enolates, was prepared (70%) from (S)-methyl p-tolyl sulfoxide. The stereoselectivity of the Yamdazyma farinosa-catalyzed
β-HYDROXY SULFOXIDE DERIVATIVES AS A POWERFUL CHIRAL PROTONATING REAGENT
Kosugi, Hiroshi,Hoshino, Kunihide,Uda, Hisashi
, p. 401 - 402 (2007/10/02)
Highly enantioselective protonation of prochiral lithium enolates using enantiomerically pure β-hydroxy sulfoxides are described.
Homochiral Perfluoroalkyl-Group-Substituted Secondary Alcohols Through Stereoselective Reduction of Perfluoroalkyl 1-(p-Tolylsulfinyl)alkyl Ketones
Bravo, Pierfrancesco,Frigerio, Massimo,Resnati, Giuseppe
, p. 955 - 960 (2007/10/02)
The reduction of some enantiomerically pure perfluoroalkyl α-(p-tolylsulfinyl) ketones was performed.Alcohols containing perfluoroalkyl and p-tolylsulfinyl groups were obtained with high diastereoselection when a phenyl residue was present on the sulfinylated carbon and with lower diastereoselection in the other cases.Removal of the chiral sulfinyl group from single diastereoisomers gave secondary alcohols containing a perfluoroalkyl group in enantiomerically pure form.
