113965-64-3Relevant academic research and scientific papers
Highly Stereoselective Asymmetric Michael Addition Reactions Employing (R;E)-3,3,3-Trifluoroprop-1-enyl p-Tolyl Sulphoxide
Yamazaki, Takashi,Ishikawa, Nobuo,Iwatsubo, Hitoshi,Kitazume, Tomoya
, p. 1340 - 1342 (2007/10/02)
(R;E)-3,3,3-Trifluoroprop-1-enyl p-tolyl sulphoxide, prepared in three steps from ethyl trifluoroacetate, showed a high degree of diastereoselectivity in Michael addition reactions with enolates; by this means, optically active trifluoromethylated organic molecules can be obtained readily in high yield as well as in high optical purity.
