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5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-4-yl)piperazin-1-yl)methyl)-N-methyl-2-nitroaniline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1140503-26-9

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1140503-26-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1140503-26-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,0,5,0 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1140503-26:
(9*1)+(8*1)+(7*4)+(6*0)+(5*5)+(4*0)+(3*3)+(2*2)+(1*6)=89
89 % 10 = 9
So 1140503-26-9 is a valid CAS Registry Number.

1140503-26-9Relevant academic research and scientific papers

Discovery of 6-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl]piperazin- 1-yl}methyl)quinoxaline(WAY-207024): An orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R)

Pelletier, Jeffrey C.,Chengalvala, Murty V.,Cottom, Joshua E.,Feingold, Irene B.,Green, Daniel M.,Hauze, Diane B.,Huselton, Christine A.,Jetter, James W.,Kopf, Gregory S.,Lundquist, Joseph T.,Magolda, Ronald L.,Mann, Charles W.,Mehlmann, John F.,Rogers, John F.,Shanno, Linda K.,Adams, William R.,Tio, Cesario O.,Wrobel, Jay E.

, p. 2148 - 2152 (2009)

A potent, highly insoluble, GnRH antagonist with a 2-phenyl-4- piperazinylbenzimidazole template and a quinoxaline-2,3-dione pharmacophore was modified to maintain GnRH antagonist activity and improve in vitro pharmaceutical properties. Structural changes

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