114085-79-9Relevant academic research and scientific papers
A New Synthesis of 1-n-Alkyl-3,5-dimethoxybenzenes (Olivetol Dimethyl Ether and Homologs)
Azzena, Ugo,Denurra, Teresa,Fenude, Emma,Melloni, Giovanni,Rassu, Gloria
, p. 28 - 30 (2007/10/02)
An efficient method is reported for the synthesis of 1-n-alkyl-3,5-dimethoxybenzenes, useful intermediates in the synthesis of cannabinoids, from the readily available and cheap 3,4,5-trimethoxybenzoic acid.The key step is the electron-transfer induced highly regioselective demethoxylation of 1-n-alkyl-3,4,5-trimethoxybenzenes.
Regioselective 4-Demethoxylation of 1-n-Alkyl-3,4,5-trimethoxybenzenes: a Key Step in the Synthesis of Olivetol and its Homologues
Azzena, Ugo,Denurra, Teresa,Melloni, Giovanni,Rassu, Gloria
, p. 1549 - 1550 (2007/10/02)
Selective removal of the 4-methoxy group in n-alkyl-3,4,5-trimethoxybenzenes was performed under electron-transfer conditions; a new synthesis of olivetol dimethyl ether is described.
