1140903-34-9Relevant academic research and scientific papers
A metal-free tandem dehydrogenative α-arylation reaction of propargylic alcohols with 2-alkynylbenzaldoximes toward the synthesis of α-(4-bromo-isoquinolin-1-yl)-propenone skeletons
Abbasi Kejani, Alireza,Alatat, Khalil,Balalaie, Saeed,Bijanzadeh, Hamid Reza,Nikbakht, Ali
supporting information, p. 579 - 583 (2022/02/01)
A tandem reaction of 2-alkynylbenzaldoximes with propargylic alcohols has been developed for the synthesis of α-(4-bromo-isoquinolin-1-yl)-propenones. Employing 2-alkynylbenzaldoximes as a precursor in the presence of Br2 generates 4-bromo-isoquinoline-N-
Generation of diverse isoquinoline N-oxides in an aqueous system
Wang, Huanhuan,Zhu, Mengdan,Ye, Shengqing,Wu, Jie
, p. 13626 - 13629 (2013/08/23)
4-Halo isoquinoline N-oxides could be synthesized efficiently via the electrophilic cyclization of 2-alkynylbenzaldoximes, involving the in situ generation of the halonium ion in water. The one-pot cyclization-Suzuki reaction in an aqueous system afforded
Three-component reactions of 2-alkynylbenzaldoximes and α,β-unsaturated carbonyl compounds with bromine or iodine monochloride
Ye, Shengqing,Gao, Ke,Wu, Jie
supporting information; experimental part, p. 1746 - 1751 (2010/09/07)
The three-component reaction of 2-alky-nylbenzaldoximes and α,β-unsaturated carbonyl compounds with bromine or iodine monochloride is described, which generates the unexpected 2-(4-halo-isoquinolin- 1-yl)ethanol derivatives in good to excellent yields
Access to functionalized isoquinoline N-oxides via sequential electrophilic cyclization/cross-coupling reactions
Ding, Qiuping,Wu, Jie
supporting information; experimental part, p. 1850 - 1854 (2009/07/24)
Electrophilic cyclization of 2-alkynylbenzaldoximes with various electrophiles leads to the formation of 4-iodoisoquinoline N-oxides or 4-bromo-isoquinoline N-oxides under mild conditions. The reaction can be transferred to highly functionalized isoquinol
