1140908-16-2

Upstream product

• 896746-85-3 (R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 896746-86-4 (R)-[3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetic acid ethyl ester 
• 1012860-22-8 N-allyl-2-[(3R)-3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetamide 
• 1012860-26-2 N-allyl-2-[(3R)-3-(hydroxymethyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetamide 
• 1012860-24-0 {(3R)-1-[2-(allylamino)-2-oxoethyl]2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}methyl[4-chloro-2-(trifluoromethyl)phenyl]carbamate 
• 292638-85-8 acrylic acid methyl ester 
• 896746-83-1 (R)-4-(2-benzoyl-phenylcarbamoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 896746-84-2 (R)-3-hydroxymethyl-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 896746-87-5 [(3R)-3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetic acid 

Downstream Products

• 1402828-87-8 (R,E)-4-{2-[3-(4-chloro-2-trifluoromethylphenylcarbamoyloxymethyl)-2-oxo-5-phenyl-2,3-dihydrobenzo[e][1,4]diazepin-1-yl]acetoxy}but-2-enoic acid 

Relevant academic research and scientific papers

NMR characterization and conformational analysis of a potent papain-family cathepsin L-like cysteine protease inhibitor with different behaviour in polar and apolar media

We recently reported the synthesis, of a potent papain-family cathepsin L-like cysteine protease inhibitor, as new lead compound for the development of new drugs that can be used as antiprotozoal agents. The investigation of its conformational profile is