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Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is a versatile chemical compound that serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a cyclopentane carboxylic acid derivative featuring an ethyl ester group and a Boc-protected amino group. The Boc group plays a crucial role in protecting the amino functionality during chemical reactions, allowing for mild deprotection conditions to reveal the free amine. Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is widely recognized for its utility as a building block in organic synthesis, enabling the creation of complex molecules with targeted biological activities. Its value extends to both medicinal and agricultural research, making it an indispensable component in the development of novel therapeutics and crop protection agents.

1140972-29-7

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1140972-29-7 Usage

Uses

Used in Pharmaceutical Synthesis:
Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs with specific therapeutic targets. Its protected amino group allows for selective reactions and subsequent deprotection to yield the desired amine-containing compounds, facilitating the creation of bioactive molecules with potential applications in treating a range of diseases.
Used in Agrochemical Development:
In the agrochemical industry, Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is utilized as a building block for the synthesis of novel agrochemicals. Its incorporation into the molecular structures of these compounds enables the development of effective crop protection agents, enhancing agricultural productivity and crop resistance to pests and diseases.
Used in Organic Synthesis:
Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is employed as a versatile building block in organic synthesis, allowing chemists to construct complex molecular architectures with precise control over the introduction of functional groups. Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate's Boc-protected amino functionality provides a platform for the synthesis of a wide array of organic molecules with tailored properties and potential applications in various fields, including materials science, catalysis, and supramolecular chemistry.
Used in Medicinal Research:
As a valuable tool in medicinal research, Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate aids in the exploration of new chemical entities with potential therapeutic effects. Its unique structural features and Boc-protected amino group enable the design and synthesis of bioactive compounds, contributing to the advancement of drug discovery and the development of innovative treatments for various medical conditions.
Used in Agricultural Research:
In agricultural research, Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate is applied as a component in the development of new agrochemicals, including herbicides, insecticides, and fungicides. Its incorporation into these compounds can enhance their efficacy and selectivity, leading to improved crop protection and increased agricultural yields.

Check Digit Verification of cas no

The CAS Registry Mumber 1140972-29-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,0,9,7 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1140972-29:
(9*1)+(8*1)+(7*4)+(6*0)+(5*9)+(4*7)+(3*2)+(2*2)+(1*9)=137
137 % 10 = 7
So 1140972-29-7 is a valid CAS Registry Number.

1140972-29-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate

1.2 Other means of identification

Product number -
Other names (1R,2S)-Ethyl 2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1140972-29-7 SDS

1140972-29-7Upstream product

1140972-29-7Relevant academic research and scientific papers

Efficient synthesis of (1R,2S) and (1S,2R)-2-aminocyclopentanecarboxylic acid ethyl ester derivatives in enantiomerically pure form

Dragovich, Peter S.,Murphy, Douglas E.,Dao, Kimkim,Kim, Sun Hee,Li, Lian-Sheng,Ruebsam, Frank,Sun, Zhongxiang,Tran, Chinh V.,Xiang, Alan X.,Zhou, Yuefen

experimental part, p. 2796 - 2803 (2009/06/28)

A 4-step synthesis of an optically active synthetic intermediate [(1R,2S)-2-(4′-fluorobenzylamino)cyclopentanecarboxylic acid ethyl ester complex with (S)-(+)-mandelic acid; compound 12, >99% de] required for the preparation of a promising HCV NS5B polymerase inhibitor is reported. This process utilizes mandelic acid as a resolving agent, which can be recovered in good yield by a simple extraction. An optimized version of the chemistry described avoids the use of chromatographic purifications making it suitable for large-scale applications. In addition, the straightforward conversion of compound 12 to enantiomerically pure (1R,2S)-2-aminocyclopentanecarboxylic acid ethyl ester and the corresponding Boc and Cbz derivatives is reported. The preparation of the enantiomer of 12 (compound 15) in enantiomerically pure form and the conversion of this entity to (1S,2R)-2-aminocyclopentanecarboxylic acid ethyl ester and the corresponding Boc and Cbz derivatives is also described.

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