197916-36-2

Basic information

• Product Name: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI)
• Synonyms: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI);Ethyl (1R,2S)-2-AMinocyclopentanecarboxylate
• CAS NO: 197916-36-2
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.2102
• Product Categories: CARBOXYLICESTER
• Mol File: 197916-36-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 213.4±33.0 °C(Predicted)
• Appearance: /
• Density: 1.045±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.10±0.40(Predicted)
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI)(197916-36-2)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI)(197916-36-2)

Safety Data

• Hazardous Substances Data: 197916-36-2(Hazardous Substances Data)

Usage

General Description

Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI) is a chemical compound with the molecular formula C7H13NO2. It is an ethyl ester derivative of 2-amino-cyclopentanecarboxylic acid, and it exists as a cis isomer. Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1R-cis)- (9CI) is used in the synthesis of various pharmaceuticals and agrochemicals, and it may also have potential applications in the field of organic chemistry. Additionally, it may have biological activities and could be of interest for further research and development in pharmaceutical and medical fields. As with any chemical compound, proper handling and storage protocols should be followed to ensure safety and minimize environmental impact.

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 1033756-47-6 (1R,25)-2-(4'-fluorobenzylamino)cyclopentanecarboxylic acid ethyl ester complex with (S)-(+)-mandelic Acid 
• 1609100-30-2 ethyl cis-2-aminocyclopentane-1-carboxylate 
• 38052-23-2 ethyl cis-2-amino-1-cyclopentane-carboxylate 
• 1140972-29-7 (1R,2S)-2-tert-butoxycarbonylaminocyclopentanecarboxylic acid ethyl ester 
• 27983-42-2 5-carboethoxypentanal 
• 5299-60-5 6-hydroxy-hexanoic acid ethyl ester 
• 39155-94-7 (1R,5S)-6-azabicyclo[3.2.0]heptan-7-one 
• 64-17-5 ethanol 
• 1346004-53-2 (1R,5S)-6-((S)-1-(4-methoxyphenyl)ethyl)-6-azabicyclo[3.2.0]heptan-7-one 
• 1346004-19-0 (S,E)-ethyl 6-((1-(4-methoxyphenyl)ethyl)imino)hexanoate 

Downstream Products

• 128052-92-6 (+)-(1S,2R)-2-aminocyclopentane-1-carboxylic acid hydrochloride 
• 128110-37-2 (1R,2S)-2-Amino-cyclopentane-1-carboxylic acid hydrochloride 
• 1609100-30-2 trans-ethyl 2-aminocyclopentanecarboxylate 

Relevant articles and documents

Expanding dynamic kinetic protocols: Transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives

Several α-alkylated β-amino esters have been obtained via DKR processes employing a kit of transaminases and isopropylamine as an amino donor in aqueous medium under mild conditions. Thus, while acyclic α-alkyl-β-keto esters afforded excellent conversions and enantioselectivities, although usually low diastereoselectivities, using more constrained cyclic β-keto esters high to excellent inductions were obtained.

Intramolecular ester enolate-imine cyclization reactions for the asymmetric synthesis of polycyclic β-lactams and cyclic β-amino acid derivatives

Enolates of chiral N-(α-methyl-p-methoxybenzyl)-ω-imino-esters undergo intramolecular cyclization reactions to afford (syn)-aza-anions of β-amino esters in high dr that cyclize to afford N-(α-methyl-p- methoxybenzyl)-β-lactams that can be readily deprotec

The first direct enzymatic hydrolysis of alicyclic β-amino esters: A route to enantiopure cis and trans β-amino acids

The first direct enzymatic method is reported for the synthesis of cis and trans βamino acid enantiomers through the lipase-catalyzed enantioselective hydrolysis of alicyclic β esters in organic media. High enantioselectivities (E usually > 001) were observed when the Candida antarctica lipase B catalyzed reactions were performed with H2O (0.5 equivalents) in iP iPr2O at 5°C. The resolved products, obtained in good yields (≥42%), could be easily separated.