1140972-74-2Relevant articles and documents
Highly enantioselective construction of axial chirality by palladium-catalyzed cycloisomerization of N- alkenyl arylethynylamides
Lmase, Hidetomo,Suda, Takeshi,Shibata, Yu,Noguchi, Keiichi,Hirano, Masao,Tanaka, Ken
, p. 1805 - 1808 (2009)
A cationic palladium(ll)/(S)-xyl-Segphos complex catalyzes enantioselective cycloisomerizations of N-alkenyl arylethynylamldes leading to axlally chlral 4-aryl-2-pyridones In high yields with high ee values. The present catalysis represents the first enantioselective construction of axial chlrallty by the transition-metal-catalyzed cyclolsomerlzatlon.