114143-75-8

Upstream product

• 78329-37-0 trans-N-(Carbobenzyloxy)-2,5-dimethylpyrrolidine 
• 7380-76-9 2-aminohex-5-ene 
• 57606-70-9 (E)-hex-5-en-2-one oxime 
• 78329-35-8 2-<(Carbobenzoxy)amino>-5-hexene 
• 59239-06-4 hex-5-en-2-one oxime 

Downstream Products

• 114143-77-0 2,5-dimethyl-1-(phenylethynyl)-pyrrolidine 

Relevant academic research and scientific papers

Chelating diamide based rate enhancement of intramolecular alkene hydroaminations catalyzed by a neutral Sc(III) complex

(Chemical Equation Presented) Neutral scandium amido complexes are viable catalysts for intramolecular alkene hydroamination. Catalytic activity is strongly coupled to the electronic character of the Sc(III) ligand environment with chelating diamide coord

Diastereoselective synthesis of 2,5-dimethylpyrrolidines and 2,6- dimethylpiperidines by reductive amination of 2,5-hexanedione and 2,6- heptanedione with hydride reagents

The reductive amination of 2,5-hexanedione and 2,6-heptanedione with ammonia and primary amines in the presence of hydride reagents afforded 2,5- dimethylpyrrolidines and 2,6-dimethylpiperidines with variable diastereoselectivity, as the cis/trans ratio was affected by the size of the ring formed and the steric and electronic properties of the nitrogen substituent. Increasing the bulkiness of the nitrogen substituent, the cis pyrrolidines and the trans-piperidines were obtained with enhanced selectivity.