114144-84-2Relevant academic research and scientific papers
Total synthesis of pteridic acid A
Yadav,Rajender,Gangadhara Rao
scheme or table, p. 348 - 350 (2010/03/25)
(Figure presented) A convergent approach to the total synthesis of pteridic acid A, having potent plant growth regulator activity, Is described. Key steps include the desymmetrization of bicyclic olefin with Brown's chiral hydroboration, acid-mediated spiroketalization, and zirconium-catalyzed ethylmagnesation protocol to Install the ethyl stereocenter at C14.
Synthesis of the C11-C23 fragment of the potent antitumor agent dlctyostatin
Dias, Luiz C.,Lima, Dimas J.P.,Goncalves, Caroline C.S.,Andricopulo, Adriano D.
supporting information; experimental part, p. 1491 - 1494 (2009/07/11)
We wish to report here our initial efforts toward the total synthesis of the potent antitumor agent dlctyostatin, describing a short and efficient synthesis of the C11-C23 fragment. Wiley-VCH Verlag GmbH & Co. KGaA.
Stereoselective total synthesis of lysocellin, the representative polyether antibiotic of the lysocellin family. Part 1. Synthesis of C1-C9 and C16-C23 subunits
Horita, Kiyoshi,Inoue, Takayuki,Tanaka, Kazuhiro,Yonemitsu, Osamu
, p. 531 - 550 (2007/10/03)
The C1-C9 (4) and C16-C23 subunits (9) of lysocellin (1), a representative polyether antibiotic, were synthesized stereoselectively from D-glucose and D-mannitol. Stereocontrolled hydroboration, Michael reaction, Grignard reaction, etc. were successfully
Total Synthesis of the Polyether Antibiotic Lysocellin. 1. Stereocontrolled Synthesis of the C1-C9 and C16-C23 Fragments
Horita, Kiyoshi,Inoue, Takayuki,Tanaka, Kazuhiro,Yonemitsu, Osamu
, p. 5537 - 5540 (2007/10/02)
Stereocontrolled synthesis of two fragments corresponding to the C1-C9 (3) and C16-C23 parts (6) of lysocellin (1) using hydroboration, Wittig-Horner reaction, and Michael reaction in the key steps is described. Key Words: Polyether antibiotic; Stereocont
