172995-81-2

Upstream product

• 144534-81-6 (2S,3S,4R)-2-tert-butyldimethylsilyloxymethyl-4-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>pentane-1,3-diol 
• 824-94-2 p-methoxybenzyl chloride 
• 114244-49-4 tert-Butyl-dimethyl-[(R)-2-((3aR,5R,6R,6aR)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-propoxy]-silane 
• 114925-45-0 (2S,3S,4R)-4-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>-2-methylpentane-1,3-diol 

Downstream Products

• 144534-82-7 (2R,3R,4S)-3-hydroxy-4-(4-methoxyphenyl)methyl-2-methylpentanal 
• 114144-84-2 (2Z,4S,5S,6S)-5-hydroxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylhept-2-enoic acid δ-lactone 
• 114144-84-2 (5S,6R)-6-((S)-1-(4-methoxybenzyloxy)propan-2-yl)-3,5-dimethyl-5,6-dihydropyran-2-one 
• 172995-69-6 (2R,3R,4R,5S)-5-(4-methoxybenzyloxymethyl)-3-methylhexane-1,2,4-triol 

Relevant academic research and scientific papers

Total Synthesis of the Polyether Antibiotic Lysocellin. 1. Stereocontrolled Synthesis of the C1-C9 and C16-C23 Fragments

Stereocontrolled synthesis of two fragments corresponding to the C1-C9 (3) and C16-C23 parts (6) of lysocellin (1) using hydroboration, Wittig-Horner reaction, and Michael reaction in the key steps is described. Key Words: Polyether antibiotic; Stereocont

Stereoselective total synthesis of lysocellin, the representative polyether antibiotic of the lysocellin family. Part 1. Synthesis of C1-C9 and C16-C23 subunits

The C1-C9 (4) and C16-C23 subunits (9) of lysocellin (1), a representative polyether antibiotic, were synthesized stereoselectively from D-glucose and D-mannitol. Stereocontrolled hydroboration, Michael reaction, Grignard reaction, etc. were successfully