114155-79-2Relevant academic research and scientific papers
Conformationally constrained renin inhibitory peptides: γ-lactam-bridged dipeptide isostere as conformational restriction
Thaisrivongs,Pals,Turner,Kroll
, p. 1369 - 1376 (2007/10/02)
A model of the conformation of the enzyme-bound inhibitor of human renin suggested the possibility of a γ-lactam conformational restriction at the P2-P3 site. Synthetic routes to these γ-lactam dipeptide isosteres and their incorpora
