114157-10-7Relevant academic research and scientific papers
Biosynthesis of Natural Products with a P-C Bond, III. - Synthesis of (R)- and (S)-(2-Aminoethyl)phosphonic Acid and Hydroxylation to (2-Amino-1-hydroxyethyl)phosphonic Acid in Acanthamoeba castellanii (Neff)
Hammerschmidt, Friedrich
, p. 955 - 960 (2007/10/02)
(Benzyloxy)acetaldehyde (4) was reduced to give (S)-(+)-2-(benzyloxy)ethanol (5) by horse liver alcohol dehydrogenase/NAD+/EtOH.This chiral alcohol was transformed into (R)- and (S)-(2-aminoethyl)phosphonic acid (AEP) (13).The enantiomer
Biosynthesis of Natural Products with a P-C Bond, II. - Hydroxylation of Deuterated (2-Aminoethyl)phosphonic Acids to (2-Amino-1-hydroxyethyl)phosphonic Acid in Acanthamoeba castellanii (Neff)
Hammerschmidt, Friedrich
, p. 537 - 542 (2007/10/02)
(2-Amino-1-hydroxyethyl)phosphonic acid (1) (OH-AEP) was transformed into the crystalline benzamide 11. (2-Amino-ethyl)phosphonic acid (-AEP) is taken up from the growth medium by Acanthamoeba castellanii, diluted by material of de-novo bi
