1142400-61-0 Usage
General Description
1-BOC-2-Chloromethyl-pyrrolidine is a type of chemical compound often used in laboratory settings and pharmaceutical research. Its systematic chemical name is tert-butyl 2-chloromethylpyrrolidine-1-carboxylate. 1-BOC-2-Chloromethyl-pyrrolidine belongs to the group of organic compounds known as pyrrolidines, which are compounds containing a pyrrolidine ring, a five-membered saturated ring with one nitrogen atom and four carbon atoms. It is a relatively complex molecule and significant in the chemical industry. Its main use is as an intermediate in organic synthesis, facilitating the creation of more complex molecules in the development of new pharmaceuticals and other compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1142400-61-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,2,4,0 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1142400-61:
(9*1)+(8*1)+(7*4)+(6*2)+(5*4)+(4*0)+(3*0)+(2*6)+(1*1)=90
90 % 10 = 0
So 1142400-61-0 is a valid CAS Registry Number.
1142400-61-0Relevant articles and documents
Triphosgene-amine base promoted chlorination of unactivated aliphatic alcohols
Villalpando, Andres,Ayala, Caitlan E.,Watson, Christopher B.,Kartika, Rendy
, p. 3989 - 3996 (2013/06/04)
Unactivated α-branched primary and secondary aliphatic alcohols have been successfully transformed into their corresponding alkyl chlorides in high yields upon treatment with a mixture of triphosgene and pyridine in dichloromethane at reflux. These mild chlorination conditions are high yielding, stereospecific, and well tolerated by numerous sensitive functionalities. Furthermore, no nuisance waste products are generated in the course of the reactions.
An efficient route to alkyl chlorides from alcohols using the complex TCT/DMF
De Luca, Lidia,Giacomelli, Giampaolo,Porcheddu, Andrea
, p. 553 - 555 (2007/10/03)
(formula presented) Efficient conversion of alcohols and β-amino alcohols to the corresponding chlorides (and bromides) can be carried out at room temperature in methylene chloride, using 2,4,6-trichloro[1,3,5]triazine and N,N-dimethyl formamide. This procedure can also be applied to optically active carbinols.
