1142947-11-2

Basic information

• Product Name: tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate
• Synonyms: tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate
• CAS NO: 1142947-11-2
• Molecular Weight: 560.72
• Mol File: 1142947-11-2.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate(1142947-11-2)
• EPA Substance Registry System: tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate(1142947-11-2)

Safety Data

• Hazardous Substances Data: 1142947-11-2(Hazardous Substances Data)

Upstream product

• 1078151-34-4 5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid 
• 1142945-83-2 ⁽⁰⁸¹⁾C₀₇₅₀₄ 

Downstream Products

• 1142947-96-3 N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-4-(4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.